Example from a Bio 2 class on the tongue rolling trait.
Known information: Tongue rolling is through to be inherited by a dominant allele (R)
A survey of a class 22 people was taken and the following results were found:
4 people can't roll their tongue (rr - genotype)
18 people can roll their tongue (RR + Rr - genotypes)
Calculating the Allele Frequencies
Let p stand for the dominant allele (R) and q stand for (r).
Since the total number of alleles in the population is made up of p+q
p+q=1
Each individual has two alleles, frequency of RR + Rr + rr = 1. Therefore we can express this equation as: p² + 2pq + q² = 1
We know that 8 alleles out of 44 are rr, so q² = 8/44 = 0.18 so q = square root of 0.18 = 0.42
Now we can solve for p. p = 1 - q = 1 - 0.42= 0.58
We can now calculate how many people in the class are likely:
Example from a Bio 2 class on the tongue rolling trait.
Known information: Tongue rolling is through to be inherited by a dominant allele (R)
A survey of a class 22 people was taken and the following results were found:
Calculating the Allele Frequencies
Let p stand for the dominant allele (R) and q stand for (r).Since the total number of alleles in the population is made up of p+q
p+q=1
Each individual has two alleles, frequency of RR + Rr + rr = 1. Therefore we can express this equation as: p² + 2pq + q² = 1